Refsum综合征又称遗传性共济失调性多发性神经炎。现将我院发现的一例报告如下。王×,男,19岁,以四肢末端针刺样疼痛伴行走不稳20天,于1982年4月15日入院。患者从1982年3月上旬起双下肢末端针刺样疼痛,数日延及双上肢,同时行走不稳。痛以晚间为重,休息无好转。8年前两耳进行性听力减退。父母非近亲婚配。其外祖母曾因双下肢瘫,发病一年死亡。体检:体温37.4℃,心率110次,呼吸27次,血压 Refsum syndrome, also known as hereditary ataxia polyneuritis. Now I found a hospital report is as follows. Wang ×, male, 19 years old, acupuncture-like pain in the extremities with unstable walking 20 days, was admitted on April 15, 1982. Patients from the beginning of March 1982 since the end of double-acupuncture acupuncture pain, a few days and double upper extremity delay, while walking unstable. Pain in the evening as a priority, rest no improvement. 8 years ago both ears progressive hearing loss. Parents non-relatives marriage. His grandmother had double leg paralysis, the incidence of one year of death. Physical examination: body temperature 37.4 ℃, heart rate 110 times, breathing 27 times, blood pressure