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Purpose To report a patient with severe corneal and conjunctival toxicity from long-te rm,habitual use of hy-drogen peroxide as an eye wash.Desig n Observational case report.Intervention and testing serial examinations of the cornea,conjunctiva,and ocul ar adnexa were done.Penetrating keratoplasty with amniotic membrane transplantation was performed.Main outcome measures Ocular inflammation,pain,and visu al acuity outcome.Results Bilateral corneal and conju nctival inflammation and scarring mimicking ocular-cicatricial pemphigoid were noted.Formation of a descemetocele after starting treat-ment with low-dose topical steroids required emergent penetrating keratoplasty with amni otic membrane trans-plantation.Conclusions This is the first reported case of ocular surface toxicity in a patient after deliberate chronic use of high-dose hydrogen peroxide.It highlights the value of obtaining a thorough medical and social history and the importance of direct questio ning about the use of any medications or agents on the eyes before making a diagnosis or initiating therapy.
Purpose To report a patient with severe corneal and conjunctival toxicity from long-te rm, habitual use of hy-drogen peroxide as an eye wash. Designer’s Observational case report. Practice and testing serial examinations of the cornea, conjunctiva, and ocul arnexnexa were done. Penetrating keratoplasty with amniotic membrane transplantation was performed. Main outcome measures Ocular inflammation, pain, and visu al acuity outcome. Results Bilateral corneal and conju nctival inflammation and scarring mimicking ocular-cicatricial pemphigoid were noted. Formation of a descemetocele after starting treat -ment with low-dose topical steroids required emergent penetrating keratoplasty with amniotic membrane trans-plantation. Confclusions This is the first reported case of ocular surface toxicity in a patient after deliberate chronic use of high-dose hydrogen peroxide. It highlights the value of Obtain a thorough medical and social history and the importance of direct questio ning about the use of any edications or agents on the eyes before making a diagnosis or initiating therapy.