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本文报告我院30年来经病理证实的8例恶性胸膜间皮细胞瘤。其中男6例,女2例,年龄18～63岁。临床表现:胸痛8例,发热、消瘦和呼吸困难7例,咳嗽6例,杵状指(趾)2例,声音嘶哑1例。6例以胸痛为首发症状。7例首次胸腔穿刺即为血性胸液,另1例先为黄色液体,以后也转为血性。3例胸液找到癌细胞,1例为不典型间皮细胞,因此,胸液细胞学检查结合病史有一定参考价值。3例胸膜活检阳性,其中2例肯定诊断(肉瘤型和上皮型各1例),另1例只肯定恶性细胞浸润,结合病史方诊断本病。
This article reports 8 cases of malignant pleural mesothelioma demonstrated by pathology in our hospital over the past 30 years. Including 6 males and 2 females, aged 18 to 63 years old. Clinical manifestations: 8 cases of chest pain, 7 cases of fever, weight loss and dyspnea, 6 cases of cough, 2 cases of clubbing (toe), 1 case of hoarseness. Six patients had chest pain as the first symptom. In 7 cases, the first thoracentesis was bloody pleural fluid, and the other case was yellow liquid first, and later became bloody. Three cases of thoracic fluid found cancer cells, and one case was atypical mesothelial cells. Therefore, pleural cytology combined with medical history has certain reference value. 3 cases of pleural biopsy were positive, of which 2 cases were definitely diagnosed (1 case of sarcoma type and epithelial type), and the other one only confirmed malignant cell infiltration, combined with history to diagnose the disease.