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目的：研究红细胞CR1分子免疫粘附活性在急、慢性乙肝病程发展中的意义。方法：采用红细胞CR1免疫粘附功能试验，测定急、慢性乙型肝炎患者红细胞C3b受体花环(E-C3bRR)及免疫复合物（E－ICR）。结果：与正常对照组比较，急、慢性乙肝患者都不同程度地出现E－C3bRR下降及E－ICR升高的现象；急性乙肝患者在急性期，其红细胞CR1免疫粘附功能明显下降，于恢复期基本恢复正常；轻、中度慢性乙肝患者的肝功能正常与否，对其红细胞CR1免疫粘附活性有明显影响（P＜0．01）；重度慢性乙肝患者其红细胞CR1免疫粘附功能下降最明显。结论：急、慢性乙型肝炎患者其红细胞CR1免疫粘附功能状况与其发病机制及预后有明显相关性（R=0．8546），值得进一步深入研究。
Objective: To study the significance of erythrocyte CR1 molecule immunoadhesion activity in the development of acute and chronic hepatitis B course. Methods: Erythrocyte erythrocyte C3b receptor rosette (E-C3bRR) and immune complex (E-ICR) were measured in erythrocyte CR1 immunoadhesion function test in patients with acute and chronic hepatitis B patients. Results: In acute and chronic hepatitis B patients, the decrease of E-C3bRR and the increase of E-ICR were observed to some extent. In the acute phase of acute hepatitis B, the erythrocyte CR1 immunoadsorption function was significantly decreased, (P <0.01). The CR1 immunoreactivity of erythrocytes in severe chronic hepatitis B patients was decreased The most obvious. Conclusion: The erythrocyte CR1 immunoadhesive function in patients with acute and chronic hepatitis B has a significant correlation with its pathogenesis and prognosis (R = 0.8546), which deserves further study.