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目的：探讨脑梗死的磁共振灌注加权成像（ＰＷＩ）表现并评价ＰＷＩ在不同时期脑梗死诊断中的应用价值。材料和方法：应用梯度回波ＥＰＩ（平面回波）序列对１９例脑梗死患者进行了２６例次注射造影剂后的ＰＷＩ。通过工作站重建相对局部脑血容量（ｒＣＢＶ）图和造影剂平均通过时间（ＭＴＴ）图。计算脑梗死中心区和边缘区与对侧相应部位的ｒＣＢＶ比值和 ＭＴＴ比值，并分析ＰＷＩ表现与 ＭＲＡ（１９例次）表现之间的关系。结果：除恢复期以外，脑梗死病灶中心多数表现为ｒＣＢＶ减少和ＭＴＴ增加；ＭＲＡ显示有血管闭塞或严重狭窄的脑梗死较ＭＲＡ未见血管异常的脑梗死之病灶中心ｒＣＢＶ减少和ＭＴＴ增加更为显著。结论：ＰＷＩ可以反映脑梗死区的血流动力学改变信息，与常规ＭＲＩ相结合，可同时反映脑梗死的形态和功能变化。
Objective: To investigate the perfusion-weighted imaging (PWI) performance of cerebral infarction and evaluate the value of PWI in the diagnosis of cerebral infarction at different stages. Materials and Methods: PWI was performed in 26 patients with 19 cerebral infarctions using a gradient echo EPI (Plane Echo) sequence. Relative local cerebral blood volume (rCBV) maps and mean contrast time of treatment (MTT) maps were reconstructed through the workstation. The ratios of rCBV and MTT in the central and border regions of cerebral infarction and contralateral side were calculated, and the relationship between PWI and MRA (19 cases) was analyzed. Results: In addition to the recovery period, most of the focal cerebral infarction center showed decreased rCBV and increased MTT; MRA showed decreased infarct size or increase of MTT in patients with cerebral infarction or severe stenosis compared with those without MRA Significant. Conclusion: PWI can reflect the hemodynamic changes of cerebral infarction area information, combined with conventional MRI, which can simultaneously reflect the morphological and functional changes of cerebral infarction.