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众所周知,先天性腭裂小儿,无论在手术前或手术后,易患肺炎、扁桃体炎、急性呼吸道疾病以及鼻炎等。作者认为,其原因不仅是由于腭裂引起的解剖和功能的障碍,而且是由于这些小儿的免疫系统有缺陷。本文研究先天性腭裂小儿的细胞免疫、体液免疫、补体及唾液中Ig的情况,共检查40例先天性腭裂小儿,同时检查80例5～7岁健康小儿作对照。检查结果发现,先天性腭裂小儿手术前,白细胞、T细胞,活化T细胞和B细胞的绝对数减少,这提示细胞免疫功能缺陷,且呈联合免疫缺陷(T和B细胞同时减少),
As we all know, children with congenital cleft palate, both in preoperative or postoperative surgery, susceptible to pneumonia, tonsillitis, acute respiratory diseases and rhinitis. The authors believe that the reason is not only due to the anatomy and function of the cleft palate caused by obstacles, but also because of these children’s immune system defects. In this paper, we study the cellular immunity, humoral immunity, complement and salivary Ig in children with congenital cleft palate. Totally 40 children with congenital cleft palate were examined, and 80 healthy children aged 5 to 7 years were examined as controls. The results showed that the absolute number of white blood cells, T cells, activated T cells and B cells before surgery in children with congenital cleft palate decreased, suggesting a deficit in cellular immune function with a combination of immunodeficiency (simultaneous reduction of T and B cells)