糖尿病已经成为继肿瘤、心血管疾病之后第三大严重威胁人类健康的慢性疾病,全世界有3亿多人患有糖尿病,近年来中国糖尿病的发病率呈快速增长态势,糖尿病大血管病变是糖尿病死亡的主要原因,因而已成为国内外密切关注的疑难病症和亟待解决的重要课题。花生四烯酸(arachidonic acid,AA)是生物体内含量最丰富,其代谢产物最具生物活性的小分子物质之一。其代谢产物在众多生理及 Diabetes has become the third most serious chronic disease that threatens human health after cancer and cardiovascular disease. More than 300 million people in the world have diabetes. In recent years, the incidence of diabetes in China has shown a rapid growth. Diabetic macroangiopathy is diabetes The main reason of death, which has become a close concern at home and abroad difficult illness and an important issue to be solved. Arachidonic acid (arachidonic acid, AA) is one of the most abundant small molecules with the most biological activity in the body. Its metabolites in many physiological and