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对湖北省 1995～ 1999年分离到脊髓灰质炎 (脊灰 )疫苗株病毒的 32例急性弛缓性麻痹 (AFP)病例进行了流行病学分析。 32例分布在 2 5个县 (市、区 ) ,发病时间无明显的聚集趋势 ,≤ 3岁儿童占 87 5 % ,未免疫和未全程免疫的占 6 5 4% ,Ⅱ型病毒占 5 3 1%。 32例中有 2例可诊断为服苗相关病例 ,另有 5例怀疑为疫苗接触者相关病例 ,其特点是 :①病例分散分布 ;②病例年龄均 <3岁 ;③临床特征有发热 ,非对称性弛缓性麻痹 ,临床诊断多为脊灰 ;④发病 6 0天后仍残留麻痹。
Epidemiological analysis of 32 acute flaccid paralysis (AFP) cases isolated from poliomyelitis (poliovirus) vaccine strain in Hubei Province from 1995 to 1999 was carried out. 32 cases were found in 25 counties (cities and districts), with no obvious trend of aggregation at the time of onset, 87.5% of children ≤ 3 years old, 65.4% of unimmunized and incompletely immunized children, 53 1%. 2 of 32 cases were diagnosed as vaccine-related cases, and 5 cases were suspected of vaccine-related cases, which are characterized by: ① scattered distribution of cases; ② cases were all <3 years old; ③ clinical features of fever, non Symptomatic flaccid paralysis, clinical diagnosis of mostly polio; ④ 60 days after the onset of residual paralysis.