目前研究认为视网膜色素上皮 (RPE)细胞是构成增生性视网膜疾病中增生膜的主要细胞成分。RPE细胞的增生和移行 ,使得增生组织长入玻璃体内 ,最终导致牵拉性视网膜脱离和失明。新近研究的某些生长因子在RPE细胞的增生和移行中发挥了重要作用。介绍几种主要的生长因子对RPE细胞的作用 ,为RPE细胞的实验研究和临床研究提供理论基础 Current research suggests that retinal pigment epithelium (RPE) cells are the major cellular components that make up the proliferative membrane in proliferative retinal diseases. Proliferation and migration of RPE cells allow proliferative tissues to grow into the vitreous, ultimately leading to traction retinal detachment and blindness. Some recently studied growth factors play an important role in the proliferation and migration of RPE cells. The effects of several major growth factors on RPE cells are introduced, providing a theoretical basis for the experimental research and clinical research of RPE cells