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目前,心脑血管疾病已成为世界范围内严重威胁人类健康的重大问题,人类对各种心脑血管疾病的关注程度日益密切。动脉粥样硬化(atherosclerosis,AS)是心脑血管疾病的基本、重要病理基础,由于AS的发病机制不是十分明确,成功建立AS模型是研究其发病机制及探讨治疗措施的主要、重要方法之一。
At present, cardiovascular and cerebrovascular diseases have become a serious problem that seriously threaten human health in the world. Human beings are paying close attention to various cardiovascular and cerebrovascular diseases. Atherosclerosis (AS) is a basic and important pathological basis of cardiovascular and cerebrovascular diseases. Since the pathogenesis of AS is not very clear, the successful establishment of AS model is one of the main and important methods to study its pathogenesis and explore therapeutic measures .