论文部分内容阅读
目的评价短暂性脑缺血发作(TIA)患者发生早期脑卒中的危险性及早期抗凝治疗的意义。方法对2008年1月至2010年12月住院治疗的450例TIA患者进行回顾性分析。调查TIA患者入院7 d内是否发生完全性脑卒中。结果①ABCD评分<4分的TIA患者366例,发生脑卒中21例(5.7%);评分≥4分的84例,发生脑卒中15例(17.8%)。②评分<4分TIA患者抗凝治疗93例,发生脑卒中18例(19.3%);非抗凝治疗273例,发生脑卒中3例(1.1%);评分≥4分TIA患者抗凝治疗60例,发生脑卒中12例(20.0%);非抗凝治疗24例,发生脑卒中3例(12.5%)。③频发TIA(发作频率>3次/日)50例,21例(42.0%)发生脑卒中;非频发TIA 400例,9例(2.2%)发生脑卒中,两者比较差异有统计学意义(P<0.005)。频发TIA患者抗凝治疗39例,发生脑卒中15例(38.5%);非抗凝治疗11例,发生脑卒中6例(54.5%),两者比较差异有统计学意义(P<0.005)。结论 ABCD评分可预测早期脑卒中的发生,TIA发作频率与是否发生脑卒中相关;抗凝治疗可以降低频发TIA脑卒中的发生率。
Objective To evaluate the risk of early stroke in patients with transient ischemic attack (TIA) and the significance of early anticoagulation therapy. Methods A retrospective analysis of 450 TIA patients hospitalized from January 2008 to December 2010 was performed. Investigate whether TIA patients have a complete stroke within 7 days of admission. Results ① 366 TIA patients with ABCD score <4 had 21 cases of stroke (5.7%); 84 patients with score ≥ 4 had 15 cases (17.8%) of stroke. ② score of 4 patients with TIA in 93 cases of anticoagulant therapy, stroke occurred in 18 cases (19.3%); non-anticoagulant therapy in 273 cases, stroke occurred in 3 cases (1.1%); score ≥ 4 points in patients with TIA anticoagulant therapy 60 Cases, stroke occurred in 12 cases (20.0%); non-anticoagulant therapy in 24 cases, 3 cases of stroke (12.5%). ③ In 50 cases of frequent TIA (seizure frequency> 3 times / day), stroke occurred in 21 cases (42.0%). There were 400 cases of non-frequent TIA and 9 cases (2.2%) of cerebral infarction. The difference was statistically significant Significance (P <0.005). There were 39 cases of anticoagulation in patients with TIA, 15 cases of stroke (38.5%), 11 cases of non-anticoagulant therapy and 6 cases of stroke (54.5%), the difference was statistically significant (P <0.005) . Conclusion ABCD score can predict the incidence of early stroke, TIA seizure frequency and whether the incidence of stroke; anticoagulant therapy can reduce the incidence of frequent TIA stroke.