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寻找在室温下有良好载氧性能的人工合成的载氧体,模拟血红蛋白(Hemoglobin,Hb)分子在载氧过程中各个亚基间的协同作用,是生物化学研究领域的一个重要课题.前人曾报道,一些双核钴(Ⅱ)卟啉在有机溶液中,低于0℃的条件下与O_2的结合有一定的协同作用,Hill系数n约为1.0～1.5.关于双核钴卟啉的吸氧动力学迄今未见报道.我们曾报道了一种双核钴(Ⅱ)卟啉的N,N-二甲基甲酰胺(DMF)溶液在室温下的吸氧热力学.本文报道这种配合物的DMF溶液在室温下的可逆吸氧动力学.
Looking for the synthetic oxygen carrier with good oxygen carrying capacity at room temperature and simulating the synergistic effect of each subunit of hemoglobin (Hb) molecule in oxygen carrying process are important topics in the field of biochemistry research. It has been reported that some binuclear cobalt (Ⅱ) porphyrins have a synergistic effect with O_2 in organic solution at temperatures below 0 ° C, with a Hill coefficient n of about 1.0 to 1.5. Kinetics has not been reported until now.We have reported the thermodynamics of oxygen absorption of N, N-dimethylformamide (DMF) solution of binuclear cobalt (Ⅱ) porphyrin at room temperature.We report the DMF Reversible oxygen uptake kinetics of the solution at room temperature.