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目的:评价新生儿肺炎患儿辅佐大剂量盐酸氨溴索治疗的临床疗效。方法:选取我院2011年11月~2013年11月接诊的新生儿肺炎患儿120例作为研究对象,随机均分为三组,各40例,其中研究组辅佐大剂量盐酸氨溴索治疗,对照组1采用常规剂量盐酸氨溴索治疗,对照组2采用常规治疗,对比分析三组临床治疗效果,包括发绀气促消失、肺部罗音消失、不良反应及住院天数等情况。结果:研究组患儿发绀气促消失、肺部罗音消失及住院天数情况皆明显优于对照组1与对照组2患儿,组间对比差异有统计学意义(P<0.05),而对照组1与对照组2之间并无显著性差异,无统计学意义(P﹥0.05);三组患儿在不良反应发生率上并无显著性差异(P﹥0.05)。结论:新生儿肺炎辅佐大剂量盐酸氨溴索治疗,可以取得比较明显的效果,疗效确切,临床症状改善更明显,值得临床借鉴。
Objective: To evaluate the clinical effect of adjuvant high-dose ambroxol hydrochloride in children with neonatal pneumonia. Methods: A total of 120 neonates with pneumonia admitted from November 2011 to November 2013 in our hospital were randomly divided into three groups (n = 40). The study group was given adjuvant boluses of ambroxol hydrochloride . The control group 1 was treated with ambroxol hydrochloride, while the control group 2 was treated by conventional therapy. The clinical effects of three groups were compared and analyzed, including the disappearance of cyanosis, the disappearance of pulmonary rales, adverse reactions and days of hospitalization. Results: There was a significant difference between the two groups in the study group (P <0.05), but there was no significant difference between the two groups in control group 1 and control group There was no significant difference between group 1 and control group 2 (P> 0.05). There was no significant difference in the incidence of adverse reactions among the three groups (P> 0.05). Conclusion: Neonatal pneumonia adjuvanted with large doses of ambroxol hydrochloride treatment can obtain more obvious effect, exact effect and clinical symptom improvement more obvious, it is worth for clinical reference.