[目的]建立快速测定番茄红素含量的方法。[方法]采用Waters Nova-Pak C18(3.9mm×150mmid.4μm),以甲醇∶乙腈(80∶20)为流动相,470nm为检测波长。[结果]测定番茄红素软胶囊中番茄红素的平均含量1.26%,RSD为2.5%;平均加标回收率97.7%,RSD为2.3%。[结论]该法可快速测定番茄红素样品中番茄红素的含量。 [Objective] To establish a method for rapid determination of lycopene content. [Method] Waters Nova-Pak C18 (3.9mm × 150mmid.4μm), methanol: acetonitrile (80:20) as mobile phase and 470nm as detection wavelength. [Result] The average content of lycopene in lycopene soft capsule was 1.26%, RSD was 2.5%. The average recoveries were 97.7% and the RSD was 2.3%. [Conclusion] The method could rapidly determine the content of lycopene in lycopene samples.