苯妥因属于生物利用度能受到制剂制造方法明显影响的药物。以相同剂量但牌号不同的制剂作癫痫病治疗时,常证明存有问题。过去生产者供应苯妥因钙片(制剂A),现改为苯妥因片(制剂C)。本文比较5种制剂 Phenytoin belongs to the class of drugs whose bioavailability can be significantly affected by the manufacturing method of the preparation. In the same dose but different brands of preparations for the treatment of epilepsy, often proved to be problematic. In the past, phenytoin calcium tablets (Formulation A) were supplied by the producers and now to phenytoin tablets (Formulation C). This article compares five formulations