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目的 :探讨中枢神经系统结核感染诊断。方法 :回顾性分析经尸检证实的 69例中枢神经系统结核感染病例。结果 :生前误诊 3 5例 ,误诊率 5 0 73 %。尸检发现脑膜病变为主 ,脑实质、脑室、脑血管、脊髓均受累。临床表现除脑膜刺激症、颅高压征 ,可有中枢神经系统局灶损害症状。颅高压是主要的死因 (61/ 69,88 4% )。结论 :中枢神经系统结核感染临床表现与结核病变性质、部位密切相关 ,认识其临床表现和病理特点有助提高诊断率
Objective: To investigate the diagnosis of tuberculosis in central nervous system. Methods: A retrospective analysis of 69 confirmed cases of CNS tuberculosis infection by autopsy. Results: 35 cases were misdiagnosed before birth, and the misdiagnosis rate was 5 0 73%. Autopsy found that meningeal lesions, brain parenchyma, ventricles, cerebrovascular, spinal cord involvement. In addition to clinical manifestations of meningeal irritation, epidural symptoms may have focal nervous system lesions. Cranial hypertension was the leading cause of death (61/69, 88 4%). Conclusion: The clinical manifestations of tuberculosis infection in the central nervous system are closely related to the nature and location of tuberculosis. Understanding its clinical manifestations and pathological features may improve the diagnosis rate