【摘 要】
：
A new isopimarane-type diterpene(liwariverol,1) and eight known compounds were isolated and characterized from the EtOAc extract of the whole plant oi Potamoget
【出 处】
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Chinese Chemical Letters
论文部分内容阅读
A new isopimarane-type diterpene(liwariverol,1) and eight known compounds were isolated and characterized from the EtOAc extract of the whole plant oi Potamogeton crispus.The structure of 1 was elucidated to be 17-hydroxy-8αH-isopimara-9(11),15- diene by means of spectroscopic methods.Among the isolates,crenulatoside A(2),an acyclic sesquiterpene glycoside,was found to have anti-oxidative activity with enhancement of the expression of the NAD(P)H:quinone oxidoreductase 1(NQO1) in human neuroblastoma SH-SY5Y cells at 100μmol/L after a 24-h incubation.
A new isopimarane-type diterpene (liwariverol, 1) and eight known compounds were isolated and characterized from the EtOAc extract of the whole plant oi Potamogeton crispus. The structure of 1 was elucidated to be 17-hydroxy-8αH-isopimara-9 ), 15-diene by means of spectroscopic methods. Am the isolates, crenulatoside A (2), an acyclic sesquiterpene glycoside, was found to have anti-oxidative activity with enhancement of the expression of the NAD (P) H: quinone oxidoreductase 1 (NQO1) in human neuroblastoma SH-SY5Y cells at 100 μmol / L after a 24-h incubation.
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