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目的为了解本地区孕妇产前TORCH感染的筛查情况。方法采用酶联免疫法(ELISA)检测1173例来院就诊的孕妇血清TORCH-IgM抗体水平,根据有无高危因素比较不同孕妇的血清抗体阳性率。结果高危因素组的孕妇TORCH-IgM阳性率分别为:TOX-IgM2.13%、RV-IgM1.42%、CMV-IgM4.26%、HSVⅠ-IgM2.48%、HSVⅡ-IgM2.13%;无高危因素组孕妇的TORCH-IgM抗体阳性率分别为:TOX-IgM0.56%、RV-IgM0.56%、CMV-IgM1.12%、HSVⅠ-IgM1.35%、HSVⅡ-IgM1.01%,比较高危因素组与无高危因素组各IgM阳性率CMV得P<0.01、TOX得P<0.05。结论高危因素组的孕妇CMV、TOX的阳性率较高,应常规进行TORCH-IgM筛查,以便提早干预不良妊娠,利于优生优育。
Objective To understand the screening of prenatal TORCH infection among pregnant women in this area. Methods Serum levels of TORCH-IgM antibody in 1173 pregnant women were analyzed by enzyme-linked immunosorbent assay (ELISA), and the positive rate of serum antibodies was compared with different pregnant women according to the presence or absence of high risk factors. Results The positive rates of TORCH-IgM in pregnant women at risk factors were TOX-IgM2.13%, RV-IgM1.42%, CMV-IgM4.26%, HSVⅠ-IgM2.48% and HSVⅡ-IgM2.13% The positive rates of TORCH-IgM antibodies in pregnant women at risk factors were: TOX-IgM 0.56%, RV-IgM 0.56%, CMV-IgM 1.12%, HSV I-IgM 1.35%, and HSV II-IgM 1.01% The positive rates of IgM in high-risk group and non-high-risk group were P <0.01, P <0.05 for TOX. Conclusions The positive rate of CMV and TOX in pregnant women with high risk factor group is high. TORCH-IgM screening should be conducted routinely in order to prematurely interfere with adverse pregnancy and to promote prenatal and postnatal care.