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蜂肽是从蜂毒中提取的低分子量多肽成分,对其抗炎镇痛作用与蜂毒进行比较,结果表明蜂肽抑制二甲苯性小鼠耳壳肿胀、角叉菜胶性大鼠足跖肿胀以及对热板法小鼠致痛、酒石酸锑钾致痛的抑制作用均显著大于蜂毒。而蜂肽的变应原性却显著小于蜂毒。提示蜂肽可作为蜂毒的有效成分应用于临床。
Bee bee peptide is a low molecular weight polypeptide extracted from bee venom. Its anti-inflammatory and analgesic effects were compared with bee venom. The results showed that bee peptide inhibited the swelling of the ear shell of xylene mice and carrageenan rat’s paws. Swelling and the inhibition of pain caused by hot plate method in mice and potassium tartrate caused by the inhibition were significantly greater than bee venom. The allergenicity of bee peptides was significantly less than that of bee venoms. It is suggested that bee-peptide can be used clinically as an effective component of bee venom.