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目的:了解我院2008~2010年抗精神病药应用情况及其变化趋势。方法:采用用药频度作为评价药物利用的指标,对2008~2010年我院抗精神病药的品种、销售金额、用药频度、日均用药金额、序号比等指标进行统计分析。结果:抗精神病药销售金额2008~2010年呈现上升趋势,非典型抗精神病药已成为一线药物,而典型抗精神病药的使用逐年降低。利培酮、氯氮平成为最常用的抗精神病药。结论:疗效好、不良反应少的非典型抗精神病药在临床治疗中应用越来越多,我院抗精神病药整体用量呈上升趋势。
Objective: To understand the application of antipsychotics in our hospital from 2008 to 2010 and its changing trend. Methods: The frequency of medication was used as an index to evaluate the use of drugs. Statistical analysis was carried out on the indexes of antipsychotics such as variety, sales amount, frequency of medication, average daily medication amount, serial number ratio from 2008 to 2010 in our hospital. Results: The sales amount of antipsychotic drugs showed an upward trend from 2008 to 2010, and atypical antipsychotic drugs have become the first - line drugs, while the use of typical antipsychotic drugs decreased year by year. Risperidone, clozapine as the most commonly used antipsychotics. Conclusion: Atypical antipsychotics with good curative effect and less adverse reactions are more and more used in clinical treatment. The overall dosage of antipsychotics in our hospital is on the rise.