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目的通过分析宿州市2012年上半年989例药物引起的不良反应病例报告,为本市药物安全使用提供参考依据。方法采用回顾性研究方法,对宿州市2012年1～6月份收集的989例药物病例报告进行分类、汇总及分析评价。结果涉及不良反应的药物中抗感染药物居首位,用药途径以静脉滴注为主,主要的不良反应累计系统-器官及其临床表现为皮肤及其附件损害。结论:应合理使用抗感染药物,慎重选择静脉滴注给药治疗,中药注射液的不良反应不容忽视,应进一步加强基本药物重点监测,确保公众用药安全。
Objective To analyze the case reports of 989 cases of adverse drug reactions caused by drugs in Suzhou in the first half of 2012 and provide references for the safe use of drugs in this Municipality. Methods A retrospective study was conducted to classify, summarize and analyze 989 cases of drug cases collected in Suzhou from January to June in 2012. Results Among the drugs involved in adverse reactions, anti-infective drugs ranked the first place. The main route of administration was intravenous drip. The major adverse cumulative reaction system-organ and its clinical manifestations was the skin and its accessories. Conclusion: Anti-infective drugs should be used rationally and intravenous drip therapy should be chosen carefully. Adverse reactions of traditional Chinese medicine injection should not be neglected. Key monitoring of essential drugs should be further strengthened to ensure public safety of drugs.