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1956年,Glick等首先发现鸡法氏囊与体液免疫的关系,囊切除后的雏鸡易感染鼠伤寒沙门氏菌,血清中测不出相应的抗体。据报道来亨鸡(White Leghorn)比其他品系鸡具有较强的抗感染力,其原因是此种鸡的法氏囊明显大于其他品种鸡,囊越大其血清中的抗体效价越高。近期研究表明,环境中的抗原物质,经连接泄殖腔的囊管,以泵作用机理进入囊腔,可加速抗体形成细胞
In 1956, Glick and other first discovered the relationship between chicken bursa and humoral immunity, chick-prone resection of chickens susceptible to Salmonella typhimurium, the serum can not be measured antibodies. It has been reported that White Leghorn is more resistant to infection than other strains of chickens because the bursa of the chicken is significantly larger than that of other breeds and the larger the capsule, the higher the antibody titer in the serum. Recent studies have shown that antigenic substances in the environment enter the cyst through a pump-action mechanism via the cystic duct connected to the cloaca to accelerate antibody-forming cells