目的:探讨雌激素-α,β型受体（estrogen recoptor α,β）在人胎盘滋养层细胞的表达和定位。方法:采用细胞培养结合免疫细胞化学ABC法。结果:人胎盘及培养的人胎盘绒毛合体、细胞滋养层细胞均呈雌激素α,β受体免疫反应性,雌激素受体免疫反应阳性物质定位于胞核内,细胞质为阴性。结论:人胎盘滋养层细胞存在雌激素α,β受体,这为研究雌激素对人胎盘滋养层细胞的功能调控提供了形态学依据。 Objective: To investigate the expression and localization of estrogen recoptor α (β) in human placental trophoblast cells. Methods: Cell culture combined with immunocytochemical ABC method. Results: Human placenta and cultured human placenta villi, cytotrophoblast cells showed estrogen α, β receptor immunoreactivity, estrogen receptor immunoreactive positive substance located in the nucleus, the cytoplasm was negative. CONCLUSION: Estrogen α and β receptors are present in human placental trophoblast cells, which provides a morphological basis for studying the functional regulation of human placental trophoblast cells.