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目的 :观察地尔硫对轻、中度原发性高血压 (EH)患者生活质量的影响。方法 :应用单盲法 ,通过生活质量调查表调查 12 8例轻、中度 EH患者用药前后存在躯体症状、健康愉快感、工作表现、抑郁水平、生活满意度、业余活动及认知功能等方面的情况。结果 :患者在躯体症状、健康愉快感、工作表现、认知功能等方面均有明显改善 (P <0 .0 5～ 0 .0 1) ,而对抑郁水平、业余活动及生活满意度等方面无明显影响。结论 :地尔硫可明显改善轻、中度 EH患者的生活质量。
Objective: To observe the effect of diltiazem on the quality of life in patients with mild to moderate essential hypertension (EH). Methods: One-blind method was used to investigate the physical symptoms, health and pleasure, job performance, depression, life satisfaction, leisure activities and cognitive function in 12 8 mild and moderate EH patients before and after treatment by the quality of life questionnaire Case. Results: The patients showed significant improvement in somatic symptoms, feeling of well-being, work performance and cognitive function (P <0.05-0.01), but not in terms of depression, leisure activities and life satisfaction No significant effect. Conclusion: Diltiazem can significantly improve the quality of life of mild and moderate EH patients.