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曾有作者报道子宫内膜癌病人外周血雌酮和雄烯二酮比对照组高,但未被以后作者证实.最近Judd报道如把子宫内膜癌和对照组的体重、年龄行配对时、外周血激素水平无显著差别.肿瘤病人雌酮较高认为是由于雄烯二酮在外周芳香化加强而不是卵巢分泌雄烯二酮增加.但是子宫内膜癌病人卵巢雄烯二酮分泌增高的问题实际尚未解决.本文前瞻性研究11例子宫内膜癌病人,术前均未行过放疗.10对照病人,都因良性疾病而行手术.两组病人均行子宫及双附件切除术,均未用过雌激素类制剂,绝经皆在4年以上.两组体重、身高都行配对,体表面积根据DuBois公式计算:
There have been reports of peripheral blood estrone and androstenedione in patients with endometrial cancer higher than the control group, but has not been confirmed by later authors. Judd recently reported if the endometrial cancer and control group weight, age, when paired peripheral No significant difference in blood hormone levels of tumor patients estrone is considered to be higher androstenedione in the peripheral aromatase rather than increased secretion of androstenedione.However, endometrial cancer patients ovarian androgen secrete increased problem The practice has not been resolved.In this study, 11 cases of endometrial cancer were prospectively underwent no radiotherapy before surgery.10 All of the 10 control patients underwent surgery due to benign diseases.The hysterectomy and double-attachment resection were performed in both groups, Used estrogen preparations, menopause are more than 4 years in both groups weight and height pairs, body surface area according to DuBois formula: