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126例经纤维胃镜确诊的十二指肠球部溃疡患者随机分为2组,分别以呋喃硝胺和甲氰咪胍治疗。其中呋喃硝胺组62例,甲氰咪胍组64例。呋喃硝胺剂量为每日口服300mg,甲氰咪胍每日1000mg,疗程均为6周。疗程结束后胃镜复查结果表明,呋喃硝胺组愈合54例(87.1％),甲氰咪胍组愈合44例(68.8％),前者疗效显著优于后者(P<0.025)。呋喃硝胺组未出现毒副反应,甲氰咪胍组部分病例出现副反应。故作者认为呋喃硝胺值得在临床上推广应用。
126 cases of duodenal ulcer diagnosed by fiber endoscopy were randomly divided into two groups, treated with nitrofurantoin and cimetidine. Among them, 62 cases were treated with nitrofurantoin and 64 cases were treated with cimetidine. Nitrofurantoin dose of oral daily 300mg, cimetidine daily 1000mg, treatment were 6 weeks. Gastroscopy after the end of treatment showed that 54 cases (87.1%) were cured with furanidan and 44 cases (68.8%) were cured with cimetidine. The former was significantly better than the latter (P <0.025). Nitrofuranthamine group did not appear toxic side effects, cimetidine group in some cases of side effects. Therefore, the author thinks that furanitramine deserves to be popularized and applied clinically.