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一般认为,滤泡发育需要滤泡刺激素(FSH)、雌二醇(E_2)和随后黄体生成素(LH)的分泌,在某种程度上,此结果部分通过滤泡液(FF)的激素浓度而反映。现有的资料指出,在晚期滤泡期得到的最大滤泡里FFLH浓度最高,此水平仅是血清值的30%。然而没有资料试图研究在自然排卵周期FFLH与其它激素的特征或与卵母细胞成熟的关系,由于接近月经中期血清中LH生物活性(bio LH)增加,故作者首先提出测定FF中bio LH,评价此测定是否与卵母细胞成熟相关。
It is generally accepted that follicular development requires the secretion of follicle stimulating hormone (FSH), estradiol (E 2) and subsequent luteinizing hormone (LH), in part, through the follicular fluid (FF) hormone Concentration and reflect. The available data indicate that the highest FFLH concentration in the largest follicles obtained in the late follicular phase is only 30% of the serum value. However, there are no data to investigate the relationship between FFLH and other hormones or oocyte maturation during the natural ovulation cycle. Since the LH bioactivity (serum LH) is approaching mid-menstrual serum, the authors first proposed the determination of bio-LH in FF, Whether this determination is related to oocyte maturation.