冠心病合并糖代谢紊乱临床特点及其预后分析

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目的了解冠心病患者伴或不伴有糖代谢紊乱的临床特点。方法回顾性分析868例冠心病患者的临床资料,其中A组为合并糖代谢异常者335例(38.6%),B组为糖代谢正常组533例(61.4%)。结果冠心病合并糖代谢异常组(A组)中伴高血压、脑卒中、心律失常者及病死率较糖代谢正常组(B组)高,两组比较差异有统计学意义(P<0.05)。A组介入冠状动脉多支病变明显多于B组,经统计学处理,P<0.05,差异有统计学意义。两组介入治疗的并发症发生率比较差异无统计学意义(P>0.05)。结论糖代谢异常与冠心病可能为伴发或并发关系,前者是后者的危险因素之一,糖尿病的早期诊治对冠心病的预后非常重要。冠心病合并应激性高血糖状态的患者年龄较大,病情较重,病死率高,需引起重视。 Objective To understand the clinical features of coronary heart disease patients with or without glucose metabolism disorder. Methods The clinical data of 868 patients with coronary heart disease were retrospectively analyzed. Among them, 335 patients (38.6%) in group A with abnormal glucose metabolism and 533 patients (61.4%) in group B with normal glucose metabolism. Results The patients with hypertension, stroke, arrhythmia and mortality in the group with abnormal glucose metabolism (group A) with coronary heart disease were higher than those with normal glucose metabolism (group B), the difference was statistically significant (P <0.05) . A group of coronary artery multi-vessel disease was significantly more than the B group, the statistical analysis, P <0.05, the difference was statistically significant. There was no significant difference in the complication rates between two groups (P> 0.05). Conclusion The abnormal glucose metabolism and coronary heart disease may be associated with or concurrent relationship, the former is one of the risk factors of the latter. The early diagnosis and treatment of diabetes is very important for the prognosis of coronary heart disease. Patients with coronary heart disease and stress hyperglycemia are older, more severe and have a higher case fatality rate.
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