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目的调查和分析郑州大学第三附属医院抗菌药物的使用情况,提高临床使用抗菌药物的合理性。方法采用整群抽样的方法,回顾性地调查郑州大学第三附属医院2006年11月—2008年9月住院病历2381份,分析患者抗菌药物的使用情况。结果在2381份病历中,有1536例患者使用抗菌药物,抗菌药物的使用率为64.51%;其中单联用药925例,占60.22%;二联513例,占33.40%;三~四联98例,占6.38%。应用抗菌药物前3位为头孢菌素类、大环内酯类、硝基咪唑类,外科及妇产科手术患者抗菌药物使用率为59.7%,Ⅰ类切口抗菌药物联合使用率为60.8%。结论手术科室抗菌药物使用存在问题较严重,抗菌药物合理应用亟待加强与规范。
Objective To investigate and analyze the use of antibacterials in the Third Affiliated Hospital of Zhengzhou University and to improve the rationality of clinical use of antibacterials. Methods A cluster sampling method was used to retrospectively survey 2381 medical records of patients in the Third Affiliated Hospital of Zhengzhou University from November 2006 to September 2008 to analyze the use of antibiotics in patients. Results Among the 2381 medical records, 1536 patients used antimicrobial drugs and the usage rate of antimicrobial drugs was 64.51%. Among them, 925 patients were single-drug, accounting for 60.22%; 513 patients were secondary (33.40%); 98 patients were triple to quadruple , Accounting for 6.38%. The top three antibacterials were cephalosporins, macrolides, nitroimidazoles, surgical and gynecological surgery patients with antibacterials utilization rate of 59.7%, Ⅰ type incision antibacterial drugs combined utilization rate of 60.8%. Conclusion There are more problems in the use of antimicrobial agents in surgical departments. The rational application of antimicrobial agents needs to be strengthened and standardized.