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目的:研究碳酸锂治疗偏头痛的疗效,并与尼莫地平作比较。方法:将128例偏头痛病人随机分成2组,碳酸锂组64例服用碳酸锂,每日剂量0.5~2.0g,分2~3次饭后服用,15d后改为0.5gqd,再服用15d。尼莫地平组64例服用尼莫地平30mg,tid,15d后改用30mg,qd,连用15d。结果:近期治愈率碳酸锂组与尼莫地平组分别为56%及35%(P<0.05)。总有效率碳酸锂组与尼莫地平组分别为95%及92%(P>0.05)。结论:碳酸锂治疗偏头痛不仅有效,且有较高的近期治愈率。
Objective: To study the curative effect of lithium carbonate on migraine and to compare with nimodipine. Methods: 128 migraineurs were randomly divided into two groups. In lithium carbonate group, 64 patients took lithium carbonate and the daily dose was 0.5-2.0g. The migraine patients were divided into two or three meals and then changed to 0.5gqd after 15 days. Take another 15d. Nimodipine group of 64 patients taking nimodipine 30mg, tid, 15d after the switch to 30mg, qd, once every 15d. Results: The recent cure rates for lithium carbonate and nimodipine were 56% and 35%, respectively (P <0.05). The total effective rate of lithium carbonate group and nimodipine group were 95% and 92% (P> 0.05). Conclusion: Lithium carbonate is not only effective in the treatment of migraine, but also has a high rate of recent cure.