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目的探讨老年妇女子宫内膜癌的临床与病理特征。方法对1986年至1996年在我院治疗的128例子宫内膜癌中≥60岁的44例进行回顾性分析,并与同时期≤50岁的33例子宫内膜癌做对照分析。全部手术切除标本经病理检查确诊。按FIGO分期标准进行分期。结果≥60岁组与≤50岁组临床分期分别为:Ⅱ级以上的占409%(18/44例)和333%(11/33例);组织分级G2-3分别为636%(28/44例)和455%(15/33例);子宫肌层侵肌深度大于1/2分别为636%(28/44例)和333%(11/33例)(P<001)。5年存活率分别为563%和824%(P<001)。结论≥60岁妇女子宫内膜癌通常临床分期晚、组织分化差、侵肌深、预后差。
Objective To investigate the clinical and pathological features of endometrial cancer in elderly women. Methods A retrospective analysis of 44 cases of ≥60 years old in 128 cases of endometrial carcinoma treated in our hospital from 1986 to 1996 was performed and compared with 33 cases of endometrial carcinoma of the same stage ≤50 years. All surgical specimens were confirmed by pathological examination. According to FIGO staging criteria staging. Results The clinical stage of ≥60 years old and ≤50 years old group were 409% (18/44 cases) and 333% (11/33 cases) of grade Ⅱ or higher, and the grades of G2-3 were 63 6% (28/44 cases) and 455% (15/33 cases). The depth of myometrial invasion was more than 1/2 in 636% (28/44 cases) and 333% (11 cases) respectively / 33 cases) (P <001). The 5-year survival rates were 563% and 824%, respectively (P <001). Conclusion The women with endometrial cancer more than 60 years old usually have late clinical stage, poor tissue differentiation, deep invasion and poor prognosis.