论文部分内容阅读
目的分析子痫前期高风险孕妇不同时机口服小剂量阿司匹林的预防意义。方法将子痫前期高风险孕妇64例,随机分为2组,研究组30例,孕龄≤16周开始口服阿司匹林50 mg/d,服药至孕龄28周;对照组34例,孕龄>16周以同样方式口服阿司匹林。比较2组子痫前期发生率、阴道分娩率、产后出血率、分娩孕周和新生儿体质量等情况。结果研究组子痫前期发生率低于对照组,差异有统计学意义(P<0.05);2组子痫前期发生率、阴道分娩率、产后出血率、分娩孕周和新生儿体质量比较差异均无统计学意义(P>0.05)。结论孕龄≤16周预防性应用小剂量阿司匹林在降低子痫前期发生风险中的作用优于孕龄>16周后服药患者,但服药时机对阴道分娩率、产后出血率、分娩孕周和新生儿体质量无明显影响。
Objective To analyze the preventive effect of oral low dose aspirin on pregnant women with high risk of preeclampsia. Methods Sixty-four pregnant women with high risk of preeclampsia were randomly divided into two groups. The study group consisted of 30 patients who started aspirin 50 mg / d in gestational age ≤16 weeks and were given medication until the gestational age of 28 weeks. The control group of 34 patients with gestational age> 16 weeks of oral aspirin in the same way. The incidences of preeclampsia, vaginal delivery, postpartum hemorrhage, gestational birth and neonatal weight were compared between the two groups. Results The incidence of preeclampsia in the study group was lower than that in the control group (P <0.05). The incidence of preeclampsia, vaginal delivery, postpartum hemorrhage, gestational birth weight and neonatal weight in the two groups were significantly different No statistical significance (P> 0.05). Conclusions The preventive effect of low-dose aspirin ≤16 weeks on gestational age less than 16 weeks after taking prophylaxis is better than vaginal delivery rate, postpartum hemorrhage rate, gestational age and newborn childbirth No significant effect on body weight.