恶性肉芽肿好发于面部中线。上呼吸道最常见,鼻腔、上腭、咽喉和颜面等处粘膜呈进行性坏死性肉芽肿改变,最后引起骨破坏。为探讨本病的治疗方法,现将我院1970～1986年收治的90例总结如下。 本组男性66例,女性24例。男女之比为2;75:1。年龄13～65岁,其中20～50岁者占76％。 发病部位和临床表现 原发于鼻部66例(占 Malignant granuloma occurs in the midline of the face. The upper respiratory tract is most common. The mucous membranes of the nasal cavity, palate, throat, and facial surface undergo progressive necrotic granulomatous changes, eventually causing bone destruction. In order to investigate the treatment of this disease, the 90 cases admitted to our hospital from 1970 to 1986 are summarized as follows. This group of 66 males and 24 females. The ratio between men and women is 2;75:1. Ages 13 to 65 years old, of whom 20 to 50 years old accounted for 76%. Incidence and clinical manifestations of primary origin in the nose 66 cases (accounting