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目的研究脑卒中后继发继发癫痫的发生率、类型,癫痫与卒中部位的关系,治疗和预后。方法收集我院2006年1月至2007年1月的住院和门诊脑卒中患者,及2006年1月至2007年1月大连医科大学附属二院的部分住院脑卒中患者进行回顾分析,部分患者门诊随访1年。结论210患者中出现继发性癫痫36例,占17.2%,继发性癫痫中男性21例,女性15例。年龄在48-89岁之间,脑卒中后继发性癫痫中蛛网膜下腔出血4例(11.1%),大面积脑栓塞(心源性)5例(13.9%),脑出血13例(36.1%),脑血栓形成11例(30.6%),腔隙性脑梗塞3例(8.3%)。脑卒中后继发癫痫与病灶的部位(皮质或脑脑叶)密切相关(P<0.01),且以全身发作居多,共21例,占58.3%,也可表现其他任何类型发作。在治疗上,对于发作次数不多者(2~3次),一般仅临时应用地西泮或苯巴比妥,对发作频繁者根据癫痫的发作类型给与长期的抗癫痫治疗。
Objective To study the incidence and type of secondary epilepsy after stroke, the relationship between epilepsy and stroke site, treatment and prognosis. Methods The hospitalized and outpatient stroke patients from January 2006 to January 2007 in our hospital were collected and retrospectively analyzed in some inpatients with stroke in hospital from January 2006 to January 2007 in Dalian Second Affiliated Hospital of Dalian Medical University. Followed up for 1 year. Conclusions There were 36 cases of secondary epilepsy in 210 patients (17.2%), 21 males and 15 females in secondary epilepsy. There were 4 cases (11.1%) of subarachnoid hemorrhage secondary to epilepsy after stroke, 5 cases (13.9%) of large area cerebral embolism (cardiogenic), 13 cases of cerebral hemorrhage (36.1 %), Cerebral thrombosis in 11 cases (30.6%) and lacunar infarction in 3 cases (8.3%). Epilepsy secondary to stroke was closely related to the site of the lesion (cortex or brain lobe) (P <0.01), and most of the episodes occurred in 21 patients (58.3%). Other seizures were also reported. In the treatment, for those who rarely attack (2 to 3 times), generally only temporary use of diazepam or phenobarbital, frequent seizures according to the type of epilepsy seizures to give long-term anti-epileptic treatment.