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目的:观察固本止咳平喘颗粒的止咳、化痰、平喘作用。方法:采用小鼠氨水诱咳法观察镇咳作用;采用小鼠酚红排泌法观察化痰作用;采用豚鼠卵蛋白喷雾引喘法观察平喘作用。结果:固本止咳平喘颗粒能显著地减少浓氨水引起小鼠咳嗽的次数并延长咳嗽潜伏期,能增加小鼠呼吸道的酚红排泌量,能延长豚鼠哮喘潜伏期,并能显著降低豚鼠BALF中白细胞数量。结论:固本止咳平喘颗粒具有明显止咳、化痰、平喘作用。
Objective: To observe the Guben Zhike Pingchuan Granules cough, phlegm, antiasthmatic effect. Methods: Anticancer effect was observed by using mouse ammonia cough-inducing method. The mice were treated with phenol red excretion to observe the effect of phlegm-resolving. The guinea pig ovalbumin was used to induce asthma. Results: Guben Zhikhi Pingchuan Granules can significantly reduce the number of cough caused by concentrated ammonia water and prolong the latent period of cough, increase the phenol red excretion in the respiratory tract of mice, prolong the incubation period of asthma in guinea pigs, The number of white blood cells. Conclusion: Guben Cough and Asthma Granule has obvious cough, phlegm, antiasthmatic effect.