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目的 建立复方姜黄片的质量标准.方法 采用TLC法对制剂中姜黄、川芎、胡椒进行定性鉴别;以HPLC法测定制剂中姜黄素的含量,采用Kromasil C18色谱柱(250 mm×4.6 mm,5.0 μm),以乙腈-1％醋酸溶液(55:45)为流动相,检测波长为430 nm.结果 制剂中姜黄素、川芎嗪、胡椒碱的薄层鉴别具有较好的专属性;姜黄素在14.62～292.74 μg·ml-1范围内线性关系良好,线性方程为Y=74 159X-200 122,r=0.9999,平均加样回收率与RSD分别为98.38％、0.59％.结论 所建立的标准科学合理,可用于该制剂的质量控制.“,”Objective To establish a quality standard for Fufangjianghuang tablets.Methods Curcumin,ligustrazine,and pepper in the preparation was identified by TLC,respectively.And HPLC was used to determine the contents of curcumin.The analytical column was Kromasil C18 column(250 mm × 4.6 mm,5.0 μm).The mobile phase was composed of acetonitrile-1％ glacial acetic acid(55 ∶ 45),and the detection wavelength was set at 430 nm.Results The TLCs of Curcumin,ligustrazine,and pepper have good specificity,respectively.Curcumin regression equation was Y =74 159X-200 122 and r =0.9999 in the concentration range of 14.62-292.74 μg·ml 1.And average recovery was 98.38％,and its RSD was 0.59％.Conclusion The standard can be used for the preparation of quality control.