整合素和生长因子受体参与介导细胞与细胞外基质(extracellular matri,ECM)之间的相互作用以及细胞内外的信号传递从而与细胞的分化、增殖、凋亡、迁移以及肿瘤的发生、侵袭和转移等过程有着密切的联系。整合素连接激酶(integron-linked kinase,ILK)作为一种重要的接头蛋白和信 Integrins and growth factor receptors are involved in mediating cell-to-cell extracellular matrix (ECM) interactions and signaling both inside and outside cells to differentiate, proliferate, apoptotic, migrate, and tumor And the transfer process is closely linked. Integrin-linked kinase (ILK) is an important adapter protein and signaling