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探讨胃肠病患者血清及尿液中一氧化氮 (NO)水平的变化及临床意义。方法 :收集胃肠病患者血清及尿液 ,分别检测其NO水平 ,并进行分析。结果 :急慢性胃炎及急慢性肠炎患者血清及尿液中NO水平明显高于正常健康组 ;胃癌及肠癌者血清及尿液中NO明显降低。结论 :胃肠炎患者NO含量明显增高 ,且NO增高对胃肠起损害作用 ;胃肠癌患者NO含量明显降低 ,且降低水平与病情相关。
To investigate the change of serum nitric oxide (NO) in patients with gastrointestinal diseases and its clinical significance. Methods: Serum and urine of patients with gastrointestinal diseases were collected and their NO levels were measured and analyzed. Results: The levels of NO in serum and urine in patients with acute and chronic gastritis and acute and chronic enteritis were significantly higher than those in normal healthy group. The levels of NO in serum and urine of gastric cancer and intestinal cancer were significantly decreased. CONCLUSIONS: The content of NO in patients with gastroenteritis is significantly increased, and the increased NO plays an important role in the injury of the gastrointestinal tract. The content of NO in patients with gastrointestinal cancer is significantly decreased, and the decreased level is correlated with the disease.