糖尿病足(diabetic foot,DF)是一种慢性、进行性的累及血管、神经、肌腱、骨骼的病变,常因足部感染和坏疽导致截肢致残,甚至死亡,尤其下肢动脉硬化闭塞引起足部缺血性病变是截肢致残的主要因素。本病尚无有效治疗手段,药物治疗收效甚微,介入治疗或血管搭桥手术的远期疗效不够理 Diabetic foot (DF) is a chronic and progressive disease involving the blood vessels, nerves, tendons and bones. It often leads to amputation, disability and even death due to foot infections and gangrene. In particular, occlusion of lower extremity arteriosclerosis causes foot Ischemic lesions are the main factor amputation. The disease is no effective treatment, drug treatment with little effect, long-term efficacy of interventional therapy or bypass surgery is not enough