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目的观察高血压患者应用甲磺酸氨氯地平前后血压昼夜节律变化及高血压药物时间治疗的血压控制情况并分析影响因素。方法收集2年来我科住院的高血压患者200例,根据动态血压监测结果将血压昼夜节律分为杓型,非杓型,反杓型及超杓型,按类型进行时间给药,随访2个月进行分析。结果入选病例中,正常血压节律87例,占43.5%;异常血压节律113例,占56.5%,其中非杓型占34.5%,反杓型占20%,超杓型占2%,中青年以正常血压节律为主,老年人以异常血压节律居多,治疗2个月,血压达标率72.5%,有71.68%的异常血压节律转为正常血压节律。结论高血压患者应重视血压节律的检测,强化高血压药物的时间治疗学。
Objective To observe the changes of circadian rhythm of blood pressure before and after the application of amlodipine mesylate in hypertensive patients and the control of blood pressure during the treatment of hypertensive drugs and analyze the influencing factors. Methods A total of 200 hypertensive patients admitted to our department during the past two years were collected. The circadian rhythm of blood pressure was divided into dipper, non-dipper, anti-dipper and dipper according to the results of ambulatory blood pressure monitoring. Month for analysis. Results Among the selected cases, 87 cases were normal blood pressure rhythm, accounting for 43.5%; 113 cases were abnormal blood pressure rhythm, accounting for 56.5%, of which non-dipper accounted for 34.5%, anti-dipper accounted for 20%, super dipper accounted for 2% Normal blood pressure rhythm, the elderly with abnormal blood pressure rhythm most of the treatment for 2 months, blood pressure compliance rate of 72.5%, 71.68% of abnormal blood pressure rhythm switch to normal blood pressure rhythm. Conclusion Hypertensive patients should pay attention to the detection of blood pressure rhythm and strengthen the time therapy of hypertension drugs.