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目的观察新活素治疗老年慢性充血性心力衰竭(心衰)急性加重患者的临床效果。方法选取慢性心衰急性加重老年高龄患者15例,在吸氧、强心、利尿、扩血管、抗感染等常规治疗的基础上加用新活素治疗5 d。观察患者心衰症状、左室射血分数(LVEF)、血人脑利钠肽(BNP)的变化情况。结果使用新活素治疗后同时出现尿量明显增加及心率明显下降3例,单纯尿量明显增加5例,单纯心率较前明显下降2例,治疗后总有效率为66.67%(10/15)。结论新活素具有排钠、排水、降压的作用,降低了心脏前后负荷,从而达到改善心衰症状的效果,临床用于治疗老年高龄慢性心衰急性加重患者,疗效显著。
Objective To observe the clinical effect of intravenous injection on elderly patients with acute exacerbation of chronic congestive heart failure (HF). Methods Fifteen patients with acute heart failure were randomly selected from elderly patients with chronic heart failure. The rats were treated with neomycin for 5 days on the basis of conventional therapy such as oxygen inhalation, cardiac, diuretic, vasodilator and anti-infective. The changes of heart failure symptoms, left ventricular ejection fraction (LVEF), and blood brain natriuretic peptide (BNP) were observed. Results After treatment with neomycin, urine volume increased significantly and heart rate decreased significantly in 3 cases. Simple urine output increased significantly in 5 cases. Simple heart rate decreased significantly in 2 cases. After treatment, the total effective rate was 66.67% (10/15) . Conclusion The new activin has the effect of discharging sodium, draining and depressurizing, reducing the anterior and posterior cardiac load and improving the symptoms of heart failure. It is clinically effective in treating elderly patients with acute exacerbation of chronic heart failure.