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目前英国常采用氨基糖苷类抗生素或头孢菌素分别联用灭滴灵,以预防选择性结直肠手术的感染。已有报告表明,单用头孢替坦与庆大霉素联用灭滴灵,在预防选择性结直肠手术时,效果是相同的。本文进一步研究:头孢替坦单用与头孢替坦联用灭滴灵时,预防结直肠手术的效果。总计615名接受选择性结直肠手术的患者随机分成二组。甲组315名、于麻醉时及术后12小时静滴头孢替坦2.0克;乙组300名,于麻醉时及术后12小时给予头孢替坦2.0克,另于麻醉时及术后8小时、16小时,又给予灭滴灵500毫克。结果术后可评价者总计有531名、甲组278名、乙组253名,感染率甲组47名(16.9
At present, the United Kingdom often use aminoglycoside antibiotics or cephalosporins were combined metronidazole, to prevent selective colorectal surgery infection. It has been reported that cefotetan alone and gentamicin combined with metronidazole in the prevention of selective colorectal surgery, the effect is the same. This article further study: cefoteram monotherapy and cefotetan metronidazole, the effect of preventing colorectal surgery. A total of 615 patients undergoing selective colorectal surgery were randomized into two groups. A group of 315, at the time of anesthesia and 12 hours after intravenous cefotetan 2.0 grams; 300 cases in group B, at the time of anesthesia and 12 hours after cefotetan was given 2.0 grams, and the other at anesthesia and after 8 hours , 16 hours, and give metronidazole 500 mg. Results A total of 531 evaluable postoperatively, 278 cases of Group A, 253 cases of Group B, 47 cases of infection rate of Group A (16.9