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类癌这一名词诞生于本世纪初，1907年Obern－dorfer用“karzinoid”来描述一组生长缓慢、低度恶性的肿瘤，随后发现这类肿瘤来源于消化道具有嗜银特性的Lieberkuhn肠腺。1953年Lembeck发现这类肿瘤细胞可以分泌卜羟色胺，1969年Pearse发现该类细胞具有摄取胺前体和脱羧基的作用
The term carcinoid was coined at the beginning of this century. In 1907, Obern-dorfer used “karzinoid” to describe a group of slow-growing, low-grade tumors. It was later discovered that this type of tumor originated from the Lieberkuhn’s intestinal tract with silver-like characteristics in the digestive tract. . In 1953, Lembeck discovered that these tumor cells can secrete serotonin. In 1969 Pearse discovered that this type of cells have the effect of uptake of amine precursors and decarboxylation.