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全身性淋巴瘤与白血病不同,很少累及眼睛和视神经,有时却可侵犯眼眶。分化不良型淋巴瘤可占所有眼眶恶性肿癌的10%。网状细胞肉瘤可能是最常见的眼内淋巴瘤,视网膜和玻璃体受其浸润,可产生非特异性葡萄膜炎;而患何杰釜氏淋巴瘤时则很少累及葡萄膜和视网膜。据 Williams 等人报告,在5,778例淋巴瘤病人中仅发现1例视神经受损。视神经损害在有些病例可能起源于颅内,在另一些病例认为是由软脑膜淋巴瘤并发现视神经的浸润,或是由于眼眶淋巴瘤转移而来。
Systemic lymphoma and leukemia different, rarely involving the eyes and optic nerve, and sometimes can invade the orbit. Poorly differentiated lymphoma can account for 10% of all orbital malignant tumors. Reticulo-sarcoma is probably the most common type of intraocular lymphoma with infiltration of the retina and vitreous, producing nonspecific uveitis, while rarely involving the uvea and retina with Hodgarth’s lymphoma. According to Williams et al., Only 1 case of optic nerve damage was found in 5,778 patients with lymphoma. Optic nerve damage can originate in the cranium in some cases, in other cases it is thought to be caused by leptomeningeal lymphoma and an infiltration of the optic nerve, or due to orbital lymphoma metastases.