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目的 骨肉瘤与骨骼尤文氏肉瘤是具有早期肺转移倾向的恶性侵袭性肿瘤 ,是青少年最常见的原发性骨肿瘤 ,由于治疗方面的进展 ,5年生存率已达到 70 % ,但复发的患者尚无好的挽救生命的方法 ,需要更有效的辅助性化疗 ,一些研究报告提出 HER2 /neu (c-erb B-2 )癌基因在骨肉瘤中表
Purpose Osteosarcoma and Bone Ewing’s Sarcoma is a malignant and aggressive tumor with early lung metastasis and is the most common primary bone tumor in adolescents. Due to the progress of treatment, the 5-year survival rate has reached 70%, but the recurrence of patients There is no good life-saving method that requires more effective adjuvant chemotherapy. Some studies have suggested that the HER2 / neu (c-erb B-2) oncogene in osteosarcoma