新生儿败血症发病率及病死率高。有的资料表明1‰～10‰活婴发生败血症。该文用 Aztreonam 治疗新生儿败血症,证明对革兰阴性菌包括多数假单胞菌属感染有效。该药对成人和儿童不抑制正常菌群,不干扰胆红素与白蛋白结合,因此无增加胆红素脑病的危险。病例与方法 55例新生儿败血症,足月儿37例; Neonatal sepsis morbidity and mortality. Some data show that 1 ‰ ~ 10 ‰ live baby sepsis. This article treats neonatal sepsis with Aztreonam, demonstrating efficacy against Gram-negative bacteria, including most Pseudomonas infections. The drug does not inhibit normal flora in adults and children, does not interfere with the binding of bilirubin and albumin, and therefore does not increase the risk of bilirubin encephalopathy. Cases and methods 55 cases of neonatal sepsis, full-term children in 37 cases;