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黄芫花醇剂已成功地应用于中期妊娠引产,并对其引产机理进行了一些研究。结果表明,羊膜腔内注射黄芫花醇剂可引起内源性前列腺素的释放,并被认为是宫缩发动和导致流产的主要环节,曾有报道,前列腺素是在肾上腺素能神经节前与节后连接处发生作用,它们能改变传递介质的释放,并调节肾上腺能神经效应传递的反馈作用。近年来·国外已报告了用前列腺素及其衍生物引产对妇女肾上腺素能神经系统的影响。Ogawa 等发现,静脉滴注前列腺素E(PGE)后,血压无明显下降和心率增加.血浆去甲肾上腺素(NE)水平增加174%,提示由于系统血压下降使肾上腺能活璔强。而SaArikoski 等却发现,用Sulprostone给孕妇静脉滴注后,血浆NE 水平明显下降,而血浆肾上腺素(E)水平及血压和心率却没有明显改变。提示suiprmtone 能抑制肾上腺索能神经末梢释放NE.而
Yellow Daphne genkwa alcohol has been successfully applied to the induction of labor in the second trimester, and its induction mechanism of some research. The results show that amniotic cavity injection of yellow genkwanol alcohol can cause the release of endogenous prostaglandin and is considered to be the main link of uterine contractions and lead to miscarriage. It has been reported that prostaglandins in adrenal ganglia preganglionic and section The posterior junctions play a role, they can change the release of the delivery mediator and regulate the feedback of the adrenal nerve nerve effects. In recent years, the effects of induction of labor with prostaglandins and their derivatives on the adrenergic nervous system of women have been reported abroad. Ogawa et al found no significant decrease in blood pressure and heart rate after intravenous instillation of prostaglandin E (PGE), an increase of 174% in plasma norepinephrine (NE) level, suggesting that the adrenal gland is viable due to decreased systemic blood pressure. However, SaArikoski et al. Found that the plasma NE level dropped significantly after intravenous infusion of Sulprostone to pregnant women, while plasma adrenaline (E) level and blood pressure and heart rate did not change significantly. Tip suiprmtone can inhibit the release of NE adrenal nerve endings