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目的观察卡泊芬净治疗曲霉菌肺炎的临床效果及安全性。方法采用回顾性研究,收集医院2005-01-2009-12使用卡泊芬净治疗曲霉菌肺炎住院患者22例,进行治疗前与治疗后的临床症状与体征,不良反应的观察及临床疗效、细菌清除率的分析。结果临床总有效率86.4%,细菌清除率为77.2%;不良反应发生率为9%。结论卡泊芬净治疗曲霉菌肺炎疗效好,不良反应相对较低,使用较为安全。
Objective To observe the clinical efficacy and safety of caspofungin in the treatment of Aspergillus pneumoniae. Methods A retrospective study was conducted to collect 22 patients hospitalized with Aspergillosis pneumonia with caspofungin from January 2005 to December 2009 in the hospital. The clinical symptoms and signs, adverse reactions and clinical efficacy before and after treatment were observed. Clearance rate analysis. Results The total clinical effective rate was 86.4%, bacterial clearance rate was 77.2%; adverse reaction rate was 9%. Conclusion Caspofungin treatment of Aspergillus pneumonia is effective, adverse reactions are relatively low, the use of more secure.