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目的探讨血脂对中老年人心脑血管疾病的危害。方法对948例50岁以上的中老年人,分为血脂正常组和血脂增高组,进行8年随访观察。结果血脂增高组共503例,其中总胆固醇(TCH)增高256例,三酰甘油(TG)增高169例,两项都增高161例,β-脂蛋白(LDL)增高231例,三项同时增高135例。发生冠心病145例,心肌梗死11例,脑动脉硬化66例,脑血栓35例,脑出血10例,脑梗死13例,高血压病115例,其他疾病74例,无临床诊断疾病34例。血脂正常组共445例,发生冠心病81例,心肌梗死2例,脑动脉硬化59例,脑血栓5例,脑出血1例,脑梗死2例,高血压病72例,其他疾病139例,无临床诊断疾病84例。两组发病情况,经统计学分析有显著性差异。结论血脂增高与心脑血管疾病的发生率呈正相关,血脂是诱发中老年人心脑血管疾病的一个重要因素。
Objective To investigate the risk of cardiovascular disease in middle-aged and elderly people. Methods A total of 948 middle-aged and elderly people over 50 years old were divided into two groups: normal blood lipids group and hyperlipidemia group, and were followed up for 8 years. Results There were 503 cases of hypercholesterolemia, including 256 cases of elevated total cholesterol (TCH), 169 cases of elevated triglyceride (TG), 161 cases of both increased and 231 cases of increased β-lipoprotein (LDL) 135 cases. There were 145 cases of coronary heart disease, 11 cases of myocardial infarction, 66 cases of cerebral arteriosclerosis, 35 cases of cerebral thrombosis, 10 cases of cerebral hemorrhage, 13 cases of cerebral infarction, 115 cases of hypertension, 74 cases of other diseases and 34 cases without clinical diagnosis. There were 445 cases of normal lipids, 81 cases of coronary heart disease, 2 cases of myocardial infarction, 59 cases of cerebral arteriosclerosis, 5 cases of cerebral thrombosis, 1 case of cerebral hemorrhage, 2 cases of cerebral infarction, 72 cases of hypertension, 139 cases of other diseases, No clinical diagnosis of disease in 84 cases. The incidence of two groups, the statistical analysis showed significant differences. Conclusion The increase of blood lipids is positively correlated with the incidence of cardiovascular and cerebrovascular diseases. Lipid is an important factor in inducing cardio-cerebrovascular diseases in the elderly.