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慢性阻塞性肺疾病(COPD)肺动脉高压患者肺动脉内血栓形成发生率很高,其外周静脉血中β-血栓球蛋白(β-TG)水平升高,血小板聚集增加,提示肺血管阻力增加与血小板激活有关。本文研究了血小板激活在 COPD 肺动脉高压患者中的作用。病人与方法 29例确诊的 COPD 患者,男26例,女3例,平均年龄60.2岁,均处于临床稳定状态。行右心导管检查,分别测定右室、肺动脉和肺楔压,以及动脉血气和心输出量,计算肺血管阻力,并采集右室、肺动脉、肺毛细血管及肘
Chronic obstructive pulmonary disease (COPD) pulmonary hypertension in patients with high incidence of pulmonary thrombosis, peripheral venous blood β-thromboglobulin (β-TG) levels, increased platelet aggregation, suggesting increased pulmonary vascular resistance and platelet Activation related. This article studies the role of platelet activation in COPD patients with pulmonary hypertension. Patients and Methods 29 cases of diagnosed patients with COPD, 26 males and 3 females, mean age 60.2 years, are in clinical stable state. Right ventricular catheterization was performed to measure the right ventricular, pulmonary and pulmonary wedge pressures, as well as arterial blood gas and cardiac output, to calculate pulmonary vascular resistance, and to collect the right ventricle, pulmonary arteries, pulmonary capillaries and elbows